February 17, 2011
John Crowley’s career as a biotech entrepreneur stems from the 1998 diagnosis of two of his children with Pompe disease — a fatal neuromuscular disorder. In 2006, Geeta Anand of The Wall Street Journal chronicled Crowley’s story in The Cure: How a Father Raised $100 Million — and Bucked the Medical Establishment — in a Quest to Save His Children. The book inspired the 2010 motion picture "Extraordinary Measures," starring Harrison Ford, Brendan Fraser and Keri Russell.
In 1999, Crowley became the founding president of Novazyme Pharmaceuticals, which was developing a novel treatment for Pompe disease. Today, he is president and CEO of Amicus Therapeutics Inc. He joined Amicus as a director in 2004 and became an executive with the company in 2005. Previously, he was founding president and CEO of Orexigen Therapeutics. Before that, Crowley was senior vice president at Genzyme Therapeutics, a position he assumed after overseeing the sale of Novazyme Pharmaceuticals to Genzyme in September 2001.
Before his two children were diagnosed with Pompe disease, Crowley held several senior management roles with the Bristol-Myers Squibb. Preceding his experience at BMS, he worked as a business strategy consultant for Marakon Associates. Crowley began his career as a litigation associate in the Health Care Practice Group of the Indianapolis-based law firm of Bingham, Summers, Welsh & Spilman.
Crowley is a commissioned officer in the United States Naval Reserve. He earned his bachelor’s degree from Georgetown University’s School of Foreign Service, his law degree from the University of Notre Dame and his MBA from Harvard Business School.